Author(s): Sejal Rajendra Chaudhari, Sunila A. Patil, S. P. Pawar

Email(s): sejalchaudhari429@gmail.com

DOI: 10.52711/2321-5844.2026.00007   

Address: Sejal Rajendra Chaudhari*, Sunila A. Patil, S. P. Pawar
Graduated Pharmacist, P.S.G.V.P. Mandal’s College of Pharmacy, Shahada, Maharashtra, 425409, India.
*Corresponding Author

Published In:   Volume - 17,      Issue - 1,     Year - 2026


ABSTRACT:
This study focuses on addressing uneven melanin production, a prevalent dermatological and cosmetic issue responsible for skin hyperpigmentation. Kojic acid, a well-known natural depigmenting agent, was combined with herbal extracts such as niacinamide, licorice root extract, and aloe vera to develop a topical gel aimed at enhancing skin tone and regulating melanin synthesis. The formulation was designed to optimize skin compatibility and stability by incorporating suitable gelling agents, pH adjusters, and preservatives. The gel’s characteristics were thoroughly evaluated through multiple parameters to ensure its suitability for topical application. Key evaluation criteria included clarity, physical appearance (color and consistency), homogeneity, pH measurement, spreadability, and drug content analysis. These assessments were conducted to confirm the uniformity, stability, ease of application, and effective delivery of active ingredients within the formulation. The comprehensive evaluation underscores the potential of this kojic acid-based gel combined with herbal extracts as an effective skin brightening and depigmentation product. The formulation holds promise for safe and efficient management of hyperpigmentation, making it a valuable addition to dermatological therapeutics and cosmetic skincare regimens.


Cite this article:
Sejal Rajendra Chaudhari, Sunila A. Patil, S. P. Pawar. Topical Gel Formulation of Kojic Acid with Herbal Extracts for Skin Tone Enhancement and Melanin Regulation. Research Journal of Topical and Cosmetic Sciences. 2026; 17(1):31-4. doi: 10.52711/2321-5844.2026.00007

Cite(Electronic):
Sejal Rajendra Chaudhari, Sunila A. Patil, S. P. Pawar. Topical Gel Formulation of Kojic Acid with Herbal Extracts for Skin Tone Enhancement and Melanin Regulation. Research Journal of Topical and Cosmetic Sciences. 2026; 17(1):31-4. doi: 10.52711/2321-5844.2026.00007   Available on: https://www.rjtcsonline.com/AbstractView.aspx?PID=2026-17-1-7


REFERENCES:
1.    Cabanes J, Chazarra S, Garcia-Carmona F. Kojic acid, a cosmetic skin whitening agent, is a slow-binding inhibitor of catecholase activity of tyrosinase. J Pharm Pharmacol. 1994; 46(12): 982-5.
2.    Júlia Capp Zilles, Francielli Lima dos Santos, Irene Clemes Kulkamp-Guerreiro, Renata Vidor Contri1. Biological activities and safety data of kojic acid and itsderivatives: A review. Experimental Dermatology. 1500-1521.
3.    Draelos ZD. The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. Br J Dermatol. 2002; 147(1): 20–31.
4.    Fu B, Li H, Wang X, Lee FS, Cui S. Isolation and identification of antioxidants from the roots of Glycyrrhiza uralensis by activity-guided fractionation. J Ethnopharmacol. 2005; 96(3): 441–6.
5.    Surjushe A, Vasani R, Saple DG. Aloe vera: a short review. Indian J Dermatol. 2008; 53(4): 163–6.
6.    https://en.wikipedia.org/wiki/Polyacrylic_acid.
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9.    Monika Chandrakant Farde, Bhakti Anil Gaonkar, Dharam Atul Gharat, Sakshi Pritam Gharat, Ritik Rakesh Gupta, Vinita Yadav and Sonali Uppalwar. Review Article On: Mouth Ulcer Gel. International Journal of Pharmaceutical Research and Applications.  2023; 8(2): 1361-1374.
10.    Sakshi B. Jadhav, Shivtej S. Jadhav, Sourav A. Jadhav, Trupti M. Jamadar, Vrushali S. Jamdar, P. S. Kadane. Formulation and Evaluation of Polyherbal gel for Management of Mouth Ulcer. international Journal for Multidisciplinary Research.  2024; 6(4); 1-16.
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